Caspase 1 Antikörper (N-Term, Subunit p20)
Kurzübersicht für Caspase 1 Antikörper (N-Term, Subunit p20) (ABIN3030287)
Target
Alle Caspase 1 (CASP1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term, Subunit p20
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Verwendungszweck
- Caspase-1 Antibody (p20 subunit)
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Sequenz
- LEKAQKLWKE NPSEIYPIMN T
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Aufreinigung
- Antigen affinity
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Immunogen
- An amino acid sequence from the N-terminus of mouse CASP1 (LEKAQKLWKENPSEIYPIMNT) was used as the immunogen for this Caspase-1 antibody. This sequence is from the p20 subunit.
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Isotyp
- IgG
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anti-Caspase 1 (CASP1) (AA 120-297) antibody
CASP1 Reaktivität: Schwein WB, IHC, ICC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Caspase 1 (CASP1) (AA 317-404) antibodyCASP1 Reaktivität: Human WB, IHC, ICC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Caspase 1 (CASP1) (AA 120-297) antibodyCASP1 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Caspase 1 (CASP1) (AA 119-296) antibodyCASP1 Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Caspase 1 (CASP1) (AA 1-311) antibodyCASP1 Reaktivität: Human WB, IHC, IP, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Caspase 1 (CASP1) (AA 1-100) antibodyCASP1 Reaktivität: Human WB, ELISA, IHC (p) Wirt: Maus Monoclonal 3D2 unconjugated
anti-Caspase 1 (CASP1) antibodyCASP1 Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Caspase 1 (CASP1) (AA 135-152), (N-Term) antibodyCASP1 Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Caspase 1 (CASP1) (C-Term) antibodyCASP1 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, ICC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Caspase 1 (CASP1) (pSer376) antibodyCASP1 Reaktivität: Human, Maus, Ratte WB, ELISA, ICC, IF Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- The stated application concentrations are suggested starting points. Titration of the Caspase-1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- After reconstitution, the Caspase-1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- Caspase 1 (CASP1)
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Andere Bezeichnung
- Caspase-1
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Hintergrund
- Caspase-1 is a cysteine protease that regulates inflammatory processes through its capacity to process and activate the interleukin-1-beta, IL-18, and IL-33 precursor proteins. It belongs to a family of cysteine proteases known as caspases that always cleave proteins following an aspartic acid residue. The Caspase-1 gene consists of 10 exons spanning at least 10.6 kb and is mapped to 11q23, a site frequently involved in rearrangement in human cancers, including a number of leukemias and lymphomas, by Southern DNA blot analysis of rodent-human hybrids and by in situ hybridization to normal human metaphase chromosomes. Caspase 1 has been shown to induce cell necrosis or pyroptosis and may function in various developmental stages.
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UniProt
- P29452
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Pathways
- Apoptose, Interferon-gamma Pathway, Positive Regulation of Endopeptidase Activity, Inflammasome
Target
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