Prothrombin Antikörper (AA 600-612)

Produktnummer ABIN3028573

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Prothrombin in WB. Er zeigt eine Reaktivität gegenüber Ratte.

Kurzübersicht für Prothrombin Antikörper (AA 600-612) (ABIN3028573)

Target: Prothrombin (F2) (Coagulation Factor II (thrombin) (F2))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Prothrombin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Prothrombin Antikörper

Bindungsspezifität: AA 600-612

Aufreinigung: Antigen affinity

Immunogen: Amino acids 600-612 (THVFRLKRWMQKV-rat) were used as the immunogen for this Prothrombin antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Titration of the Prothrombin antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the Prothrombin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu Prothrombin

Target: Prothrombin (F2) (Coagulation Factor II (thrombin) (F2))

Andere Bezeichnung: Prothrombin (Thrombin)

Hintergrund: F2 (Coagulation Factor II), also known as prothrombin and thrombin, is a serine protease that in humans is encoded by the F2 gene. The activated thrombin enzyme plays an important role in hemostasis and thrombosis: it converts fibrinogen to fibrin for blood clot formation, stimulates platelet aggregation, and activates coagulation factors V, VIII(F8), and XIII(F13A1). Thrombin also inhibits coagulation by Activating protein C.

UniProt: P18292

Pathways: Komplementsystem, Peptide Hormone Metabolism, Regulation of G-Protein Coupled Receptor Protein Signaling