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Prothrombin Antikörper (Middle Region)

F2 Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund, Meerschweinchen, Pferd, Schaf, Zebrafisch (Danio rerio) WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2776976
  • Target Alle Prothrombin (F2) Antikörper anzeigen
    Prothrombin (F2) (Coagulation Factor II (thrombin) (F2))
    Bindungsspezifität
    • 6
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    • 44
    • 25
    • 15
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Ratte, Maus, Rind (Kuh), Hund, Meerschweinchen, Pferd, Schaf, Zebrafisch (Danio rerio)
    Wirt
    • 46
    • 15
    • 9
    • 5
    • 2
    • 1
    • 1
    Kaninchen
    Klonalität
    • 66
    • 13
    Polyklonal
    Konjugat
    • 53
    • 12
    • 6
    • 2
    • 2
    • 2
    • 2
    Dieser Prothrombin Antikörper ist unkonjugiert
    Applikation
    • 53
    • 28
    • 26
    • 20
    • 14
    • 13
    • 11
    • 9
    • 8
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    ISDRWVLTAA HCLLYPPWDK NFTENDLLVR IGKHSRTRYE RNIEKISMLE
    Homologie
    Cow: 92%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Sheep: 93%, Zebrafish: 77%
    Produktmerkmale
    This is a rabbit polyclonal antibody against F2. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human F2
    Top Product
    Discover our top product F2 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 622 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    Prothrombin (F2) (Coagulation Factor II (thrombin) (F2))
    Andere Bezeichnung
    F2 (F2 Produkte)
    Synonyme
    PT antikoerper, RPRGL2 antikoerper, THPH1 antikoerper, Cf-2 antikoerper, Cf2 antikoerper, FII antikoerper, thrombin antikoerper, zgc:66319 antikoerper, wu:fb57c10 antikoerper, wu:fd42e09 antikoerper, wu:fd59d01 antikoerper, prothrombin antikoerper, F2 antikoerper, coagulation factor II, thrombin antikoerper, coagulation factor II antikoerper, coagulation factor II (thrombin) antikoerper, F2 antikoerper, f2 antikoerper
    Hintergrund
    Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life.Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Mutations in F2 leads to various forms of thrombosis and dysprothrombinemia. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: PT
    Protein Interaction Partner: ST13, FN1, DDIT3, ALB, F11, PROZ, ITGA2B, SERPING1, HGFAC, AKR7A2, CPB2, F2RL3, F2RL2, SERPINA5, SERPINB8, AANAT, F2RL1, F9, F8, GP1BA, KNG1, F5, C6, PLAU, THBS1, THBD, F2R, SERPINE2, F2, PROS1, AMBP, PROC, GP5, SERPINE1, SERPINB6, SPP1, IGFBP5, IGFBP3, S
    Protein Size: 622
    Molekulargewicht
    70 kDa
    Gen-ID
    2147
    NCBI Accession
    NM_000506, NP_000497
    UniProt
    P00734
    Pathways
    Komplementsystem, Peptide Hormone Metabolism, Regulation of G-Protein Coupled Receptor Protein Signaling
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