Caspase 1 Antikörper (Large Subunit, N-Term)
Kurzübersicht für Caspase 1 Antikörper (Large Subunit, N-Term) (ABIN3028535)
Target
Alle Caspase 1 (CASP1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Large Subunit, N-Term
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Verwendungszweck
- Caspase-1 Antibody (p20 subunit)
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Sequenz
- CSLEEAQRIW KQKSAEIY
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Aufreinigung
- Antigen affinity
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Immunogen
- An amino acid sequence from the N-terminus of human CASP1 (CSLEEAQRIWKQKSAEIY) was used as the immunogen for this Caspase-1 antibody. The sequence is from the large subunit.
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Isotyp
- IgG
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Applikationshinweise
- Titration of the Caspase-1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- The lyophilized Caspase-1 antibody can be stored at 4oC. After reconstitution, aliquot and store at -20oC. Repeated freeze/thaw steps should be avoided.
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- Caspase 1 (CASP1)
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Andere Bezeichnung
- Caspase-1
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Hintergrund
- Caspase-1 is a cysteine protease that regulates inflammatory processes through its capacity to process and activate the interleukin-1-beta, interleukin 18, and interleukin 33 precursor proteins. The Caspase-1 gene consists of 10 exons spanning at least 10.6 kb and is mapped to 11q23, a site frequently involved in rearrangement in human cancers, including a number of leukemias and lymphomas.
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UniProt
- P29466
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Pathways
- Apoptose, Interferon-gamma Pathway, Positive Regulation of Endopeptidase Activity, Inflammasome
Target
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