Caspase 1 Antikörper (Large Subunit, N-Term)

Produktnummer ABIN3028535

Der Kaninchen Polyklonal Anti-Caspase 1-Antikörper wurde für WB und IHC (p) validiert. Er ist geeignet, Caspase 1 in Proben von Human zu detektieren.

Kurzübersicht für Caspase 1 Antikörper (Large Subunit, N-Term) (ABIN3028535)

Target: Caspase 1 (CASP1)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Caspase 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Caspase 1 Antikörper

Bindungsspezifität: Large Subunit, N-Term

Aufreinigung: Antigen affinity

Immunogen: An amino acid sequence from the N-terminus of human CASP1 (CSLEEAQRIWKQKSAEIY) was used as the immunogen for this Caspase-1 antibody. The sequence is from the large subunit.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Titration of the Caspase-1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: The lyophilized Caspase-1 antibody can be stored at 4°C. After reconstitution, aliquot and store at -20°C. Repeated freeze/thaw steps should be avoided.

Details zu Caspase 1

Target: Caspase 1 (CASP1)

Andere Bezeichnung: Caspase-1

Hintergrund: Caspase-1 is a cysteine protease that regulates inflammatory processes through its capacity to process and activate the interleukin-1-beta, interleukin 18, and interleukin 33 precursor proteins. The Caspase-1 gene consists of 10 exons spanning at least 10.6 kb and is mapped to 11q23, a site frequently involved in rearrangement in human cancers, including a number of leukemias and lymphomas.

UniProt: P29466

Pathways: Apoptose, Interferon-gamma Pathway, Positive Regulation of Endopeptidase Activity, Inflammasome