CDK1 Antikörper

Produktnummer ABIN3026474

Produktdetails anti-CDK1 Antikörper

Target: CDK1 (Cyclin-Dependent Kinase 1 (CDK1))

Reaktivität: Human, Affe, Rind (Kuh), Nerz

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CDK1 Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Keine Kreuzreaktivität: Maus, Ratte (Rattus), Xenopus laevis, Fruchtfliege (Drosophila melanogaster), Schizosaccharomyces pombe, Yeast (Saccharomyces cerevisiae)

Produktmerkmale: This antibody recognizes a 34 kDa protein, which is identified as cyclin dependent kinase 1 (Cdk1) or p34cdc2 protein kinase. CDK1 plays a crucial role during cell division and is most active during mitosis. It is predominantly localized in the nucleus. It is a serine/threonine kinase, which is activated by cyclin, presumably by de-phosphorylation of tyrosine residues. Activated CDK1 performs specific functions during mitosis, including nuclear envelope breakdown and chromosome condensation.

Aufreinigung: Protein G purified antibody

Immunogen: Purified recombinant human Cdk1 / p34cdc2 was used as the immunogen for this Cdk1 antibody.

Klon: POH-1

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise: The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the Cdk1 antibody to be titered up or down for optimal performance.

1. Staining of FFPE tissues requires boiling tissue sections in 10  mM citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 min.\. FACS: 0.5-1 μg/million cells,IF: 1-2 μg/mL,IHC (FFPE) only: 1-2 μg/mL (1)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the Cdk1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Details zu CDK1

Target: CDK1 (Cyclin-Dependent Kinase 1 (CDK1))

Andere Bezeichnung: Cdk1 (CDK1 Produkte)

Synonyme: CDC2 antikoerper, CDC28A antikoerper, P34CDC2 antikoerper, Cdc2 antikoerper, Cdc2a antikoerper, p34 antikoerper, cdc2 antikoerper, wu:fc30e01 antikoerper, zgc:92032 antikoerper, PSTAIR antikoerper, cdc-2 antikoerper, cdc2-a antikoerper, cdc28a antikoerper, cdc2x1.1 antikoerper, p34cdc2 antikoerper, xcdc2 antikoerper, 5363 antikoerper, CDCDm antikoerper, CDK1 antikoerper, CDK1/CDC2 antikoerper, CG5363 antikoerper, Cdk-1 antikoerper, Cdk1 antikoerper, Dcdc2 antikoerper, Dm cdc2 antikoerper, DmCdc2 antikoerper, DmCdk1 antikoerper, Dmcdc2 antikoerper, Dmel\\CG5363 antikoerper, cdc antikoerper, cdc2Dm antikoerper, cdk1 antikoerper, dCdk1 antikoerper, group 4 antikoerper, l(2)31Eh antikoerper, CDC2A antikoerper, CDC2AAT antikoerper, CDK2 antikoerper, CDKA1 antikoerper, CDKA;1 antikoerper, CYCLIN-DEPENDENT KINASE A;1 antikoerper, cell division control 2 antikoerper, cdc2-b antikoerper, cdc2a antikoerper, cdc2x1.2 antikoerper, POL3 antikoerper, pold antikoerper, cyclin dependent kinase 1 antikoerper, cyclin dependent kinase like 1 antikoerper, Cell division control protein 2 1 antikoerper, cyclin-dependent kinase 1 antikoerper, cyclin-dependent kinase 1 S homeolog antikoerper, Cyclin-dependent kinase 1 antikoerper, cell division control 2 antikoerper, cell division control protein2 homolog antikoerper, cyclin-dependent kinase 1 L homeolog antikoerper, polymerase (DNA directed), delta 1, catalytic subunit L homeolog antikoerper, cyclin-dependent protein kinase Cdk1/Cdc2 antikoerper, CDK1 antikoerper, CDKL1 antikoerper, POPTR_0004s14080g antikoerper, Cdk1 antikoerper, cdk1 antikoerper, cdk1.S antikoerper, CDC2 antikoerper, cdc2 antikoerper, cdk-1 antikoerper, cdk1.L antikoerper, pold1.L antikoerper

Hintergrund: This antibody recognizes a 34  kDa protein, which is identified as cyclin dependent kinase 1 (Cdk1) or p34cdc2 protein kinase. CDK1 plays a crucial role during cell division and is most active during mitosis. It is predominantly localized in the nucleus. It is a serine/threonine kinase, which is activated by cyclin, presumably by de-phosphorylation of tyrosine residues. Activated CDK1 performs specific functions during mitosis, including nuclear envelope breakdown and chromosome condensation.

Gen-ID: 983

Pathways: Zellzyklus, Fc-epsilon Rezeptor Signalübertragung, Neurotrophin Signalübertragung, Activation of Innate immune Response, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Toll-Like Receptors Cascades, Synthesis of DNA