c-MYC Antikörper (C-Term)

Produktnummer ABIN3025307

Dieser Maus Monoklonal Antikörper detektiert spezifisch c-MYC in IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für c-MYC Antikörper (C-Term) (ABIN3025307)

Target: c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser c-MYC Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Güteklasse: Carrier-free

Klon: SPM237

Produktdetails anti-c-MYC Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: Myc Antibody (azide and preservative free)

Sequenz: AEEQKLISEE DLLRKRREQL KHKLEQLRNS CA

Keine Kreuzreaktivität: Maus, Ratte (Rattus), Huhn

Aufreinigung: Protein G affinity chromatography

Immunogen: Amino acids AEEQKLISEEDLLRKRREQLKHKLEQLRNSCA from the C-terminus were used as the immunogen for the Myc antibody.

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Myc antibody should be determined by the researcher.

1. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 min
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the Myc antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Details zu c-MYC

Target: c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))

Andere Bezeichnung: Myc

Hintergrund: Myc, or c-Myc, is involved in the control of cell proliferation and differentiation and is amplified and/or overexpressed in a variety of tumors. Over-expression of c-Myc protein occurs frequently in luminal cells of prostate intraepithelial neoplasia as well as in most primary carcinomas and metastatic disease.

UniProt: P01106

Pathways: p53 Signalweg, Zellzyklus, Sensory Perception of Sound, Transition Metal Ion Homeostasis, Mitotic G1-G1/S Phases, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Warburg Effekt