MAP2K6 Antikörper (AA 1-334)

Produktnummer ABIN3023391

Der Kaninchen Polyklonal Anti-MAP2K6-Antikörper wurde für WB und IF validiert. Er ist geeignet, MAP2K6 in Proben von Human zu detektieren. Es sind 2+ Publikationen verfügbar.

Kurzübersicht für MAP2K6 Antikörper (AA 1-334) (ABIN3023391)

Target: MAP2K6 (Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAP2K6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-MAP2K6 Antikörper

Bindungsspezifität: AA 1-334

Sequenz: MSQSKGKKRN PGLKIPKEAF EQPQTSSTPP RDLDSKACIS IGNQNFEVKA DDLEPIMELG RGAYGVVEKM RHVPSGQIMA VKRIRATVNS QEQKRLLMDL DISMRTVDCP FTVTFYGALF REGDVWICME LMDTSLDKFY KQVIDKGQTI PEDILGKIAV SIVKALEHLH SKLSVIHRDV KPSNVLINAL GQVKMCDFGI SGYLVDSVAK TIDAGCKPYM APERINPELN QKGYSVKSDI WSLGITMIEL AILRFPYDSW GTPFQQLKQV VEEPSPQLPA DKFSAEFVDF TSQCLKKNSK ERPTYPELMQ HPFFTLHESK GTDVASFVKL ILGD

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-334 of human MEK6 (NP_002749.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-MAP2K6 Antikörper (ABIN3023391)

Ma, Chen, Zhang, Ma, Yang, Zhang, Li, Xiao, Wang: "MAPK kinase 10.2 promotes disease resistance and drought tolerance by activating different MAPKs in rice." in: The Plant journal : for cell and molecular biology, Vol. 92, Issue 4, pp. 557-570, (2018) (PubMed).

Fan, Long, Yan, Wang, Shi, Bao, Hu, Li, Chen, Zheng, Yan: "Dietary leucine supplementation alters energy metabolism and induces slow-to-fast transitions in longissimus dorsi muscle of weanling piglets." in: The British journal of nutrition, Vol. 117, Issue 9, pp. 1222-1234, (2017) (PubMed).

Details zu MAP2K6

Target: MAP2K6 (Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6))

Andere Bezeichnung: MAP2K6

Hintergrund: This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis.,MAP2K6,MAPKK6,MEK6,MKK6,PRKMK6,SAPKK-3,SAPKK3,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,Kinase,Tyrosine kinases,ErbB-HER Signaling Pathway,MAPK-P38 Signaling Pathway,Cell Biology & Developmental Biology,Cell Cycle,Cell cycle inhibitors,Cytoskeleton,Actins,TGF-b-Smad Signaling Pathway,Immunology & Inflammation,B Cell Receptor Signaling Pathway,IL-6 Receptor Signaling Pathway,Toll-like Receptor Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,TLR Signaling,Neuroscience,Neurodegenerative Diseases,MAP2K6

Molekulargewicht: 31 kDa/37 kDa

Gen-ID: 5608

UniProt: P52564

Pathways: MAPK Signalweg, TLR Signalweg, Activation of Innate immune Response, Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades