Connexin 43/GJA1 Antikörper (AA 233-382)

Produktnummer ABIN3023088

Der Kaninchen Polyklonal Anti-Connexin 43/GJA1-Antikörper wurde für WB validiert. Er ist geeignet, Connexin 43/GJA1 in Proben von Human zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für Connexin 43/GJA1 Antikörper (AA 233-382) (ABIN3023088)

Target: Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Connexin 43/GJA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Connexin 43/GJA1 Antikörper

Bindungsspezifität: AA 233-382

Sequenz: FKGVKDRVKG KSDPYHATSG ALSPAKDCGS QKYAYFNGCS SPTAPLSPMS PPGYKLVTGD RNNSSCRNYN KQASEQNWAN YSAEQNRMGQ AGSTISNSHA QPFDFPDDNQ NSKKLAAGHE LQPLAIVDQR PSSRASSRAS SRPRPDDLEI

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 233-382 of human GJA1 (NP_000156.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-Connexin 43/GJA1 Antikörper (ABIN3023088)

Wang, Li, Song, Chen: "Gastric electrical stimulation improves enteric neuronal survival." in: International journal of molecular medicine, Vol. 40, Issue 2, pp. 438-446, (2018) (PubMed).

Details zu Connexin 43/GJA1

Target: Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))

Andere Bezeichnung: GJA1

Hintergrund: This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. The encoded protein is the major protein of gap junctions in the heart that are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. A related intronless pseudogene has been mapped to chromosome 5. Mutations in this gene have been associated with oculodentodigital dysplasia, autosomal recessive craniometaphyseal dysplasia and heart malformations.,GJA1,AVSD3,CMDR,CX43,EKVP,GJAL,HLHS1,HSS,ODDD,PPKCA,EKVP3,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Gap Junctions,Cytoskeleton,Immunology & Inflammation,Cardiovascular,Heart,Cardiac arrhythmias,GJA1

Molekulargewicht: 43 kDa

Gen-ID: 2697

UniProt: P17302

Pathways: MAPK Signalweg, Myometrial Relaxation and Contraction, Cell-Cell Junction Organization