Phospholipase C beta 1 Antikörper (AA 917-1216)
Kurzübersicht für Phospholipase C beta 1 Antikörper (AA 917-1216) (ABIN3022699)
Target
Alle Phospholipase C beta 1 (PLCB1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 917-1216
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Sequenz
- KSFVKLQKKH YKEMKDLVKR HHKKTTDLIK EHTTKYNEIQ NDYLRRRAAL EKSAKKDSKK KSEPSSPDHG SSTIEQDLAA LDAEMTQKLI DLKDKQQQQL LNLRQEQYYS EKYQKREHIK LLIQKLTDVA EECQNNQLKK LKEICEKEKK ELKKKMDKKR QEKITEAKSK DKSQMEEEKT EMIRSYIQEV VQYIKRLEEA QSKRQEKLVE KHKEIRQQIL DEKPKLQVEL EQEYQDKFKR LPLEILEFVQ EAMKGKISED SNHGSAPLSL SSDPGKVNHK TPSSEELGGD IPGKEFDTPL
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 917-1216 of human PLCB1 (NP_056007.1).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid freeze / thaw cycles
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Phospholipase C beta 1 (PLCB1) (phospholipase C, beta 1 (phosphoinositide-Specific) (PLCB1))
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Andere Bezeichnung
- PLCB1
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Hintergrund
- The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. This gene is activated by two G-protein alpha subunits, alpha-q and alpha-11. Two transcript variants encoding different isoforms have been found for this gene.,PLCB1,EIEE12,PI-PLC,PLC-154,PLC-I,PLC-beta-1,PLC154,PLCB1A,PLCB1B,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,Cell Biology & Developmental Biology,Cytoskeleton,Actins,Endocrine & Metabolism,Lipid Metabolism,AMPK Signaling Pathway,Neuroscience,Neurodegenerative Diseases,PLCB1
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Molekulargewicht
- 133 kDa/138 kDa
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Gen-ID
- 23236
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UniProt
- Q9NQ66
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Pathways
- WNT Signalweg, AMPK Signaling, Thyroid Hormone Synthesis, Inositol Metabolic Process, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, Proton Transport, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events, G-protein mediated Events
Target
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