Caspase 6 Antikörper (AA 24-293)
Kurzübersicht für Caspase 6 Antikörper (AA 24-293) (ABIN3022545)
Target
Alle Caspase 6 (CASP6) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 24-293
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Sequenz
- AFYKREMFDP AEKYKMDHRR RGIALIFNHE RFFWHLTLPE RRGTCADRDN LTRRFSDLGF EVKCFNDLKA EELLLKIHEV STVSHADADC FVCVFLSHGE GNHIYAYDAK IEIQTLTGLF KGDKCHSLVG KPKIFIIQAC RGNQHDVPVI PLDVVDNQTE KLDTNITEVD AASVYTLPAG ADFLMCYSVA EGYYSHRETV NGSWYIQDLC EMLGKYGSSL EFTELLTLVN RKVSQRRVDF CKDPSAIGKK QVPCFASMLT KKLHFFPKSN
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Kreuzreaktivität
- Human, Maus
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Produktmerkmale
- Polyclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 24-293 of human Caspase-6 (NP_001217.2).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000,IF,1:50 - 1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid freeze / thaw cycles
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Caspase 6 (CASP6) (Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))
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Andere Bezeichnung
- CASP6
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Hintergrund
- This gene encodes a member of the cysteine-aspartic acid protease (caspase) family of enzymes. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic acid residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in multiple transcript variants that encode different isoforms.,CASP6,MCH2,caspase-6,Caspase-6 p18,Caspase-6,Signal Transduction,ErbB-HER Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Caspases,Inhibition of Apoptosis,Death Receptor Signaling Pathway,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,CASP6
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Molekulargewicht
- 22 kDa/33 kDa
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Gen-ID
- 839
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UniProt
- P55212
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Pathways
- Apoptose, Caspase Kaskade in der Apoptose
Target
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