TLR5 Antikörper (AA 714-858)

Produktnummer ABIN3022439

Dieses Anti-TLR5-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von TLR5 in WB und IHC. Geeignet für Human.

Kurzübersicht für TLR5 Antikörper (AA 714-858) (ABIN3022439)

Target: TLR5 (Toll-Like Receptor 5 (TLR5))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TLR5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-TLR5 Antikörper

Bindungsspezifität: AA 714-858

Sequenz: HLDTQYSDQN RFNLCFEERD FVPGENRIAN IQDAIWNSRK IVCLVSRHFL RDGWCLEAFS YAQGRCLSDL NSALIMVVVG SLSQYQLMKH QSIRGFVQKQ QYLRWPEDLQ DVGWFLHKLS QQILKKEKEK KKDNNIPLQT VATIS

Kreuzreaktivität: Human

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 714-858 of human TLR5 (NP_003259.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu TLR5

Target: TLR5 (Toll-Like Receptor 5 (TLR5))

Andere Bezeichnung: TLR5

Hintergrund: This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct pathogen-associated molecular patterns that are expressed on infectious agents. The protein encoded by this gene recognizes bacterial flagellin, the principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB, which in turn activates a host of inflammatory-related target genes. Mutations in this gene have been associated with both resistance and susceptibility to systemic lupus erythematosus, and susceptibility to Legionnaire disease.,MELIOS,SLE1,SLEB1,TIL3,TLR5,Immunology & Inflammation,Toll-like Receptor Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,TLR Signaling,TLR5

Molekulargewicht: 97 kDa

Gen-ID: 7100

UniProt: O60602

Pathways: TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades