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Cyclin H Antikörper (AA 1-323)

Der Kaninchen Polyklonal Anti-Cyclin H-Antikörper wurde für WB und IP validiert. Er ist geeignet, Cyclin H in Proben von Human zu detektieren.
Produktnummer ABIN3021259

Kurzübersicht für Cyclin H Antikörper (AA 1-323) (ABIN3021259)

Target

Alle Cyclin H (CCNH) Antikörper anzeigen
Cyclin H (CCNH)

Reaktivität

  • 85
  • 48
  • 29
  • 7
  • 5
  • 5
  • 5
  • 4
  • 4
  • 4
  • 2
  • 1
  • 1
Human

Wirt

  • 71
  • 16
Kaninchen

Klonalität

  • 64
  • 23
Polyklonal

Konjugat

  • 52
  • 6
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
Dieser Cyclin H Antikörper ist unkonjugiert

Applikation

  • 56
  • 34
  • 21
  • 19
  • 16
  • 6
  • 6
  • 5
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunoprecipitation (IP)
  • Bindungsspezifität

    • 12
    • 10
    • 8
    • 8
    • 7
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-323

    Sequenz

    MYHNSSQKRH WTFSSEEQLA RLRADANRKF RCKAVANGKV LPNDPVFLEP HEEMTLCKYY EKRLLEFCSV FKPAMPRSVV GTACMYFKRF YLNNSVMEYH PRIIMLTCAF LACKVDEFNV SSPQFVGNLR ESPLGQEKAL EQILEYELLL IQQLNFHLIV HNPYRPFEGF LIDLKTRYPI LENPEILRKT ADDFLNRIAL TDAYLLYTPS QIALTAILSS ASRAGITMES YLSESLMLKE NRTCLSQLLD IMKSMRNLVK KYEPPRSEEV AVLKQKLERC HSAELALNVI TKKRKGYEDD DYVSKKSKHE EEEWTDDDLV ESL

    Kreuzreaktivität

    Human

    Produktmerkmale

    Polyclonal Antibodies

    Aufreinigung

    Affinity purification

    Immunogen

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-323 of human Cyclin H (NP_001230.1).

    Isotyp

    IgG
  • Applikationshinweise

    WB,1:500 - 1:2000,IP,1:50 - 1:200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid freeze / thaw cycles

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Avoid freeze / thaw cycles.
  • Target

    Cyclin H (CCNH)

    Andere Bezeichnung

    CCNH

    Hintergrund

    The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, thus functions as a CDK-activating kinase (CAK). This cyclin and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes. They participate in two different transcriptional regulation processes, suggesting an important link between basal transcription control and the cell cycle machinery. A pseudogene of this gene is found on chromosome 4. Alternate splicing results in multiple transcript variants.,CCNH,CAK,CycH,p34,p37,cyclin-H,Epigenetics & Nuclear Signaling,DNA Damage & Repair,Cell Biology & Developmental Biology,Cell Cycle,Cyclins,CCNH

    Molekulargewicht

    37 kDa

    Gen-ID

    902

    UniProt

    P51946

    Pathways

    Zellzyklus, Mitotic G1-G1/S Phases, M Phase
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