MCL-1 Antikörper (AA 120-220)
Kurzübersicht für MCL-1 Antikörper (AA 120-220) (ABIN3020788)
Target
Alle MCL-1 (MCL1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 120-220
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Sequenz
- MSPEEELDGY EPEPLGKRPA VLPLLELVGE SGNNTSTDGS LPSTPPPAEE EEDELYRQSL EIISRYLREQ ATGAKDTKPM GRSGATSRKA LETLRRVGDG V
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Kreuzreaktivität
- Human, Maus
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Produktmerkmale
- Polyclonal Antibodies
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Immunogen
- A synthetic peptide corresponding to a sequence within amino acids 120-220 of human MCL1 (NP_068779.1).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:100 - 1:200,IF,1:50 - 1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid freeze / thaw cycles
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- MCL-1 (MCL1) (Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1))
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Andere Bezeichnung
- MCL1
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Hintergrund
- This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing.,MCL1,BCL2L3,EAT,MCL1-ES,MCL1L,MCL1S,Mcl-1,TM,bcl2-L-3,mcl1/EAT,MCL1,Cancer,Invasion and Metastasis,Cell Biology & Developmental Biology,Apoptosis,Bcl 2 family,Mitochondrial Control of Apoptosis,Inhibition of Apoptosis,Endocrine & Metabolism,Immunology & Inflammation,IL-6 Receptor Signaling Pathway,MCL1
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Molekulargewicht
- 28 kDa/37 kDa
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Gen-ID
- 4170
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UniProt
- Q07820
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Pathways
- MAPK Signalweg
Target
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