CDK1 Antikörper (AA 208-258)
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- Target Alle CDK1 Antikörper anzeigen
- CDK1 (Cyclin-Dependent Kinase 1 (CDK1))
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Bindungsspezifität
- AA 208-258
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CDK1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
- Sequenz
- SEIDQLFRIF RALGTPNNEV WPEVESLQDY KNTFPKWKPG SLASHVKNLD E
- Kreuzreaktivität
- Human, Maus, Ratte
- Produktmerkmale
- Polyclonal Antibodies
- Aufreinigung
- Affinity purification
- Immunogen
- A synthetic peptide corresponding to a sequence within amino acids 208-258 of human CDK1 (NP_001777.1).
- Isotyp
- IgG
- Top Product
- Discover our top product CDK1 Primärantikörper
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- Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:200,IP,1:50 - 1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid freeze / thaw cycles
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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A New Perspective for Osteosarcoma Therapy: Proteasome Inhibition by MLN9708/2238 Successfully Induces Apoptosis and Cell Cycle Arrest and Attenuates the Invasion Ability of Osteosarcoma Cells in ..." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 41, Issue 2, pp. 451-465, (2017) (PubMed).
: "Prevention of Simvastatin-Induced Inhibition of Tendon Cell Proliferation and Cell Cycle Progression by Geranylgeranyl Pyrophosphate." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 149, Issue 2, pp. 326-34, (2016) (PubMed).
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A New Perspective for Osteosarcoma Therapy: Proteasome Inhibition by MLN9708/2238 Successfully Induces Apoptosis and Cell Cycle Arrest and Attenuates the Invasion Ability of Osteosarcoma Cells in ..." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 41, Issue 2, pp. 451-465, (2017) (PubMed).
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- Target
- CDK1 (Cyclin-Dependent Kinase 1 (CDK1))
- Andere Bezeichnung
- CDK1 (CDK1 Produkte)
- Hintergrund
- The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,CDK1,CDC2,CDC28A,P34CDC2,Epigenetics & Nuclear Signaling,Signal Transduction,G protein signaling,Kinase,Serine/threonine kinases,ErbB-HER Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,Centrosome,G2/M DNA Damage Checkpoint,Microtubules,Immunology & Inflammation,Neuroscience,Neurodegenerative Diseases,CDK1
- Molekulargewicht
- 27 kDa/34 kDa
- Gen-ID
- 983
- UniProt
- P06493
- Pathways
- Zellzyklus, Fc-epsilon Rezeptor Signalübertragung, Neurotrophin Signalübertragung, Activation of Innate immune Response, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Toll-Like Receptors Cascades, Synthesis of DNA
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