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ATG5 Antikörper (AA 1-275)

Der Kaninchen Polyklonal Anti-ATG5-Antikörper wurde für WB, IHC und IF validiert. Er ist geeignet, ATG5 in Proben von Human zu detektieren. Es sind 6+ Publikationen verfügbar.
Produktnummer ABIN3020674

Kurzübersicht für ATG5 Antikörper (AA 1-275) (ABIN3020674)

Target

Alle ATG5 Antikörper anzeigen
ATG5 (ATG5 Autophagy Related 5 (ATG5))

Reaktivität

  • 145
  • 56
  • 42
  • 6
  • 6
  • 5
  • 5
  • 5
  • 4
  • 4
  • 4
  • 3
  • 3
  • 2
Human

Wirt

  • 80
  • 63
  • 4
  • 1
Kaninchen

Klonalität

  • 78
  • 70
Polyklonal

Konjugat

  • 69
  • 8
  • 7
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser ATG5 Antikörper ist unkonjugiert

Applikation

  • 106
  • 76
  • 50
  • 40
  • 17
  • 15
  • 14
  • 14
  • 13
  • 9
  • 8
  • 5
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • Bindungsspezifität

    • 45
    • 16
    • 9
    • 6
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-275

    Sequenz

    MTDDKDVLRD VWFGRIPTCF TLYQDEITER EAEPYYLLLP RVSYLTLVTD KVKKHFQKVM RQEDISEIWF EYEGTPLKWH YPIGLLFDLL ASSSALPWNI TVHFKSFPEK DLLHCPSKDA IEAHFMSCMK EADALKHKSQ VINEMQKKDH KQLWMGLQND RFDQFWAINR KLMEYPAEEN GFRYIPFRIY QTTTERPFIQ KLFRPVAADG QLHTLGDLLK EVCPSAIDPE DGEKKNQVMI HGIEPMLETP LQWLSEHLSY PDNFLHISII PQPTD

    Kreuzreaktivität

    Human, Maus, Ratte

    Produktmerkmale

    Polyclonal Antibodies

    Aufreinigung

    Affinity purification

    Immunogen

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-275 of human ATG5 (NP_004840.1).

    Isotyp

    IgG
  • Applikationshinweise

    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid freeze / thaw cycles

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Avoid freeze / thaw cycles.
  • Chen, Wu, Sang, Wang, Zong, Sun, Liu, Zhao: "The lncRNA HULC functions as an oncogene by targeting ATG7 and ITGB1 in epithelial ovarian carcinoma." in: Cell death & disease, Vol. 8, Issue 10, pp. e3118, (2018) (PubMed).

    Li, Zhao, Wang, Shao, Wang, Wang, Xing: "Regulation of autophagy factors by oxidative stress and cardiac enzymes imbalance during arsenic or/and copper induced cardiotoxicity in Gallus gallus." in: Ecotoxicology and environmental safety, Vol. 148, pp. 125-134, (2018) (PubMed).

    Sun, Li, Zhao, Wang, Liu, Shao, Xue, Xing: "Synergistic effect of copper and arsenic upon oxidative stress, inflammation and autophagy alterations in brain tissues of Gallus gallus." in: Journal of inorganic biochemistry, Vol. 178, pp. 54-62, (2018) (PubMed).

    Shao, Zhao, Wang, Liu, Zong, Xing: "Copper-Mediated Mitochondrial Fission/Fusion Is Associated with Intrinsic Apoptosis and Autophagy in the Testis Tissues of Chicken." in: Biological trace element research, (2018) (PubMed).

    Shao, Zhao, Wang, Liu, Li, Luo, Xing: "The apoptosis in arsenic-induced oxidative stress is associated with autophagy in the testis tissues of chicken." in: Poultry science, Vol. 97, Issue 9, pp. 3248-3257, (2018) (PubMed).

    Gou, Zhao, Fan, Yuan, Liao, He, Xu, Chen: "Autophagy induces apoptosis and death of T lymphocytes in the spleen of pigs infected with CSFV." in: Scientific reports, Vol. 7, Issue 1, pp. 13577, (2017) (PubMed).

  • Target

    ATG5 (ATG5 Autophagy Related 5 (ATG5))

    Andere Bezeichnung

    ATG5

    Hintergrund

    The protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular processes, including autophagic vesicle formation, mitochondrial quality control after oxidative damage, negative regulation of the innate antiviral immune response, lymphocyte development and proliferation, MHC II antigen presentation, adipocyte differentiation, and apoptosis. Several transcript variants encoding different protein isoforms have been found for this gene.,ATG5,APG5,APG5-LIKE,APG5L,ASP,hAPG5,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Autophagy,Ubiquitin,Endocrine & Metabolism,Mitochondrial metabolism,Immunology & Inflammation,Cardiovascular,Heart,ATGs,ATG5

    Molekulargewicht

    22 kDa/32 kDa

    Gen-ID

    9474

    UniProt

    Q9H1Y0

    Pathways

    Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Autophagie
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