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Complement Factor B Antikörper (AA 80-420)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Complement Factor B in WB, IHC, IP und IF. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN3015550

Kurzübersicht für Complement Factor B Antikörper (AA 80-420) (ABIN3015550)

Target

Alle Complement Factor B (CFB) Antikörper anzeigen
Complement Factor B (CFB)

Reaktivität

  • 89
  • 48
  • 40
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 112
  • 20
  • 3
  • 1
Kaninchen

Klonalität

  • 112
  • 21
  • 2
Polyklonal

Konjugat

  • 66
  • 23
  • 16
  • 8
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Complement Factor B Antikörper ist unkonjugiert

Applikation

  • 105
  • 52
  • 44
  • 29
  • 25
  • 18
  • 13
  • 10
  • 9
  • 6
  • 5
  • 4
  • 3
  • 2
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)
  • Bindungsspezifität

    • 15
    • 10
    • 10
    • 6
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 80-420

    Sequenz

    GSWSTLKTQD QKTVRKAECR AIHCPRPHDF ENGEYWPRSP YYNVSDEISF HCYDGYTLRG SANRTCQVNG RWSGQTAICD NGAGYCSNPG IPIGTRKVGS QYRLEDSVTY HCSRGLTLRG SQRRTCQEGG SWSGTEPSCQ DSFMYDTPQE VAEAFLSSLT ETIEGVDAED GHGPGEQQKR KIVLDPSGSM NIYLVLDGSD SIGASNFTGA KKCLVNLIEK VASYGVKPRY GLVTYATYPK IWVKVSEADS SNADWVTKQL NEINYEDHKL KSGTNTKKAL QAVYSMMSWP DDVPPEGWNR TRHVIILMTD GLHNMGGDPI TVIDEIRDLL YIGKDRKNPR E

    Kreuzreaktivität

    Human, Maus, Ratte

    Produktmerkmale

    Polyclonal Antibodies

    Aufreinigung

    Affinity purification

    Immunogen

    Recombinant fusion protein containing a sequence corresponding to amino acids 80-420 of human Complement Factor B (NP_001701.2).

    Isotyp

    IgG
  • Applikationshinweise

    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:20 - 1:50

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Buffer

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Avoid freeze / thaw cycles.
  • Target

    Complement Factor B (CFB)

    Andere Bezeichnung

    CFB

    Hintergrund

    This gene encodes complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. This cluster includes several genes involved in regulation of the immune reaction. Polymorphisms in this gene are associated with a reduced risk of age-related macular degeneration. The polyadenylation site of this gene is 421 bp from the 5' end of the gene for complement component 2.,CFB,AHUS4,ARMD14,BF,BFD,CFAB,CFBD,FB,FBI12,GBG,H2-Bf,PBF2,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,CFB

    Molekulargewicht

    68 kDa/85 kDa

    Gen-ID

    629

    UniProt

    P00751

    Pathways

    Komplementsystem, Proton Transport, Ribonucleoside Biosynthetic Process
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