Survivin Antikörper (AA 125-142)

Produktnummer ABIN289546

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Survivin in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Survivin Antikörper (AA 125-142) (ABIN289546)

Target: Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Survivin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Survivin Antikörper

Bindungsspezifität: AA 125-142

Spezifität: This antibody will recognize wild type Rev protein produced from both in vivo (expression in COS, CV-1, HeLa cell lines) and in vitro (E. coli bacterial expressionsystem and translation products). Very low crossreactivity with other E. coli proteinson western blot. Crossreactivity with other GST fusion proteins will occur unless preabsorbed against GST.

Kreuzreaktivität: Maus, Ratte (Rattus)

Kreuzreaktivität (Details): This antibody reacts with residues 125-142 EETAKKVRRAIEQLAAMD of the human Survivin protein. Cross reacts with mouse and rat Survivin (88% sequenceidentity).

Aufreinigung: Affinity chromatography purified

Immunogen: Survivin antibody was raised in rabbit using AA 125-142 EETAKKVRRAIEQLAAMD of the human survivin protein as the immunogen.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:1,000
Optimal conditions should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: Lot specific

Buffer: Supplied in PBS, with 0.02 % NaN3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Details zu Survivin

Target: Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))

Andere Bezeichnung: Survivin

Hintergrund: Survivin is a human gene encoding a structurally unique IAP apoptosis inhibitor. Present during fetal development, survivin is undetectable in terminally differentiated adult tissues. However, survivin becomes prominently expressed in transformed cell lines and in all the most common human cancers of lung, colon, pancreas, prostate and breast, in vivo.

Pathways: Apoptose, Zellzyklus, Nuclear Hormone Receptor Binding