IL1A Antikörper

Produktnummer ABIN289345

Produktdetails anti-IL1A Antikörper

Target: IL1A (Interleukin 1 alpha (IL1A))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL1A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Blocking Antibody (Inhibition)

Aufreinigung: Purified

Immunogen: IL1 alpha antibody was raised in rabbit using highly pure recombinant human IL-1-alpha as the immunogen.

Anwendungsinformationen

Applikationshinweise: ELISA: 0.5-2 µg/mL, Inhibition: 1-2 µg/mL, WB: 0.1-0.2 µg/mL
Optimal conditions should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute in sterile water at a concentration of >0.2 mg/mL.

Konzentration: Lot specific

Buffer: Lyophilized from PBS, pH 7.2.

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.

Details zu IL1A

Target: IL1A (Interleukin 1 alpha (IL1A))

Andere Bezeichnung: IL1 alpha (IL1A Produkte)

Synonyme: IL-1A antikoerper, IL1 antikoerper, IL1-ALPHA antikoerper, IL1F1 antikoerper, IL-6 antikoerper, Il-1a antikoerper, IL-1 alpha antikoerper, IL-1alpha antikoerper, L1A antikoerper, interleukin 1 alpha antikoerper, interleukin 6 antikoerper, IL1A antikoerper, IL6 antikoerper, Il1a antikoerper

Hintergrund: IL1a is a non-secreted proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL1a and IL1beta binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL2 release, B-cell maturation and proliferation, mitogenic FGFlike activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL1beta is a secreted cytokine, IL1a is predominantly a cell-associated cytokine.

Molekulargewicht: 17.7 kDa (predicted detection band MW)

Pathways: NF-kappaB Signalweg, Autophagie, Cancer Immune Checkpoints