RPS6KB2 Antikörper (Center)
Kurzübersicht für RPS6KB2 Antikörper (Center) (ABIN2855216)
Target
Alle RPS6KB2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Center
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Kreuzreaktivität
- Maus, Ratte (Rattus), Rind (Kuh)
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Kreuzreaktivität (Details)
- Mouse (96 %), Rat (96 %), Bovine (97 %)
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Produktmerkmale
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Rabbit Polyclonal antibody to S6K2 (ribosomal protein S6 kinase, 70 kDa, polypeptide 2)
S6K2 antibody [N1C1] -
Aufreinigung
- Purified by antigen-affinity chromatography.
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Immunogen
- Recombinant protein encompassing a sequence within the center region of human S6K2. The exact sequence is proprietary.
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Isotyp
- IgG
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Applikationshinweise
- Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
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Kommentare
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Positive Control: HeLa
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.72 mg/mL
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Buffer
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
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Konservierungsmittel
- Thimerosal (Merthiolate)
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Vorsichtsmaßnahmen
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- RPS6KB2 (Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 2 (RPS6KB2))
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Andere Bezeichnung
- S6K2
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Hintergrund
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This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates the S6 ribosomal protein and eucaryotic translation initiation factor 4B (eIF4B). Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation.
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Molekulargewicht
- 53 kDa
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Gen-ID
- 6199
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Pathways
- PI3K-Akt Signalweg, RTK Signalweg, AMPK Signaling, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung
Target
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