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AXL Antikörper (C-Term)

Der Kaninchen Polyklonal Anti-AXL-Antikörper wurde für WB und IHC (p) validiert. Er ist geeignet, AXL in Proben von Human zu detektieren.
Produktnummer ABIN2855015

Kurzübersicht für AXL Antikörper (C-Term) (ABIN2855015)

Target

Alle AXL Antikörper anzeigen
AXL (AXL Receptor tyrosine Kinase (AXL))

Reaktivität

  • 137
  • 67
  • 57
  • 6
  • 5
  • 4
  • 4
  • 1
  • 1
Human

Wirt

  • 123
  • 20
  • 4
  • 3
  • 1
Kaninchen

Klonalität

  • 121
  • 26
  • 2
Polyklonal

Konjugat

  • 64
  • 12
  • 9
  • 8
  • 6
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
Dieser AXL Antikörper ist unkonjugiert

Applikation

  • 107
  • 63
  • 34
  • 26
  • 26
  • 22
  • 12
  • 11
  • 6
  • 6
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Güteklasse

KO Validated
  • Bindungsspezifität

    • 19
    • 19
    • 19
    • 15
    • 11
    • 9
    • 8
    • 8
    • 8
    • 6
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Kreuzreaktivität

    Human

    Produktmerkmale

    Rabbit Polyclonal antibody to AXL (AXL receptor tyrosine kinase)
    AXL antibody [C2C3], C-term

    Aufreinigung

    Purified by antigen-affinity chromatography.

    Immunogen

    Recombinant protein encompassing a sequence within the C-terminus region of human AXL. The exact sequence is proprietary.

    Isotyp

    IgG
  • Applikationshinweise

    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    Kommentare

    Positive Control: H1299 , AXL transfected 293T , HeLa

    Validation: KO/KD, Overexpression

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    0.34 mg/mL

    Buffer

    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

    Konservierungsmittel

    Thimerosal (Merthiolate)

    Vorsichtsmaßnahmen

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target

    AXL (AXL Receptor tyrosine Kinase (AXL))

    Andere Bezeichnung

    AXL receptor tyrosine kinase

    Hintergrund

    The protein encoded by this gene is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, this protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation and can also mediate cell aggregation by homophilic binding. Alternatively spliced transcript variants encoding different isoforms have been identified.

    Cellular Localization: Membrane, Single-pass type I membrane protein

    Molekulargewicht

    98 kDa

    Gen-ID

    558

    UniProt

    P30530

    Pathways

    RTK Signalweg, Cellular Response to Molecule of Bacterial Origin
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