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Growth Hormone 1 Antikörper

Der Kaninchen Polyklonal Anti-Growth Hormone 1-Antikörper wurde für WB und IHC (p) validiert. Er ist geeignet, Growth Hormone 1 in Proben von Human zu detektieren.
Produktnummer ABIN2854976

Kurzübersicht für Growth Hormone 1 Antikörper (ABIN2854976)

Target

Alle Growth Hormone 1 (GH1) Antikörper anzeigen
Growth Hormone 1 (GH1)

Reaktivität

  • 136
  • 20
  • 14
  • 11
  • 8
  • 8
  • 6
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
Human

Wirt

  • 87
  • 79
  • 2
  • 1
  • 1
Kaninchen

Klonalität

  • 99
  • 71
Polyklonal

Konjugat

  • 102
  • 13
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Growth Hormone 1 Antikörper ist unkonjugiert

Applikation

  • 92
  • 91
  • 39
  • 38
  • 30
  • 22
  • 20
  • 13
  • 13
  • 12
  • 12
  • 9
  • 7
  • 6
  • 6
  • 5
  • 4
  • 4
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Kreuzreaktivität

    Human

    Produktmerkmale

    Rabbit Polyclonal antibody to Growth Hormone (growth hormone 1)
    Growth Hormone antibody [N1C3]

    Aufreinigung

    Purified by antigen-affinity chromatography.

    Immunogen

    Recombinant protein encompassing a sequence within the center region of human Growth Hormone. The exact sequence is proprietary.

    Isotyp

    IgG
  • Applikationshinweise

    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    Kommentare

    Positive Control: 293T

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

    Konservierungsmittel

    Thimerosal (Merthiolate)

    Vorsichtsmaßnahmen

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target

    Growth Hormone 1 (GH1)

    Andere Bezeichnung

    growth hormone 1

    Hintergrund

    The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation, an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature.

    Cellular Localization: Secreted

    Molekulargewicht

    25 kDa

    Gen-ID

    2688

    UniProt

    P01241

    Pathways

    NF-kappaB Signalweg, JAK-STAT Signalweg, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Response to Growth Hormone Stimulus, Regulation of Hormone Biosynthetic Process
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