TET2 Antikörper (AA 1165-1215) (AbBy Fluor® 594)
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- Target Alle TET2 Antikörper anzeigen
- TET2 (Tet Methylcytosine Dioxygenase 2 (TET2))
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Bindungsspezifität
- AA 1165-1215
- Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TET2 Antikörper ist konjugiert mit AbBy Fluor® 594
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Applikation
- Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human TET2
- Isotyp
- IgG
- Top Product
- Discover our top product TET2 Primärantikörper
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anti-Tet Methylcytosine Dioxygenase 2 (TET2) (AA 1833-2002) antibody
TET2 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Tet Methylcytosine Dioxygenase 2 (TET2) antibodyTET2 Reaktivität: Human WB, IHC, ELISA, FACS, ICC Wirt: Maus Monoclonal 5H8C7 unconjugated
anti-Tet Methylcytosine Dioxygenase 2 (TET2) antibodyTET2 Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Tet Methylcytosine Dioxygenase 2 (TET2) (AA 1833-2002) antibodyTET2 Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Tet Methylcytosine Dioxygenase 2 (TET2) antibodyTET2 Reaktivität: Human ELISA, FACS Wirt: Maus Monoclonal 5H8B3 unconjugated
anti-Tet Methylcytosine Dioxygenase 2 (TET2) (AA 1833-2002) antibodyTET2 Reaktivität: Human IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Tet Methylcytosine Dioxygenase 2 (TET2) (AA 528-554), (N-Term) antibodyTET2 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB37907 unconjugated
anti-Tet Methylcytosine Dioxygenase 2 (TET2) (Internal Region) antibodyVerified TET2 Reaktivität: Human IHC, ELISA, FACS Wirt: Ziege Polyclonal unconjugated
anti-Tet Methylcytosine Dioxygenase 2 (TET2) (AA 1-300) antibodyTET2 Reaktivität: Human WB, IP Wirt: Maus Monoclonal 21F11 unconjugated
anti-Tet Methylcytosine Dioxygenase 2 (TET2) (AA 528-554) antibodyTET2 Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- IF(IHC-P)(1:50-200)
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at 4°C
- Haltbarkeit
- 12 months
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- Target
- TET2 (Tet Methylcytosine Dioxygenase 2 (TET2))
- Andere Bezeichnung
- TET2 (TET2 Produkte)
- Hintergrund
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Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and plays a key role in active DNA demethylation. Has a preference for 5-hydroxymethylcytosine in CpG motifs. Also mediates subsequent conversion of 5hmC into 5-formylcytosine (5fC), and conversion of 5fC to 5-carboxylcytosine (5caC). Conversion of 5mC into 5hmC, 5fC and 5caC probably constitutes the first step in cytosine demethylation. Methylation at the C5 position of cytosine bases is an epigenetic modification of the mammalian genome which plays an important role in transcriptional regulation. In addition to its role in DNA demethylation, also involved in the recruitment of the O-GlcNAc transferase OGT to CpG-rich transcription start sites of active genes, thereby promoting histone H2B GlcNAcylation by OGT.
Synonyms: MDS, KIAA1546, Methylcytosine dioxygenase TET2, TET2, Nbla00191 - Gen-ID
- 54790
- UniProt
- Q6N021
- Pathways
- Warburg Effekt
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