ATF3 Antikörper (C-Term)

Produktnummer ABIN2799112

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch ATF3 in WB und FACS. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für ATF3 Antikörper (C-Term) (ABIN2799112)

Target: ATF3 (Activating Transcription Factor 3 (ATF3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATF3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Produktdetails anti-ATF3 Antikörper

Bindungsspezifität: AA 140-168, C-Term

Verwendungszweck: Rabbit Anti-Human ATF3 (C-term) Antibody

Immunogen: This ATF3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 140-168 amino acids from the C-terminal region of human ATF3.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Western Blot, Flow Cytometry
Recommended Dilutions
WB: 1:1000, FC: 1:10-50ATF3 Antibody (C-term) .FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.300 mg/mL

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C (short-term), -20°C (long-term)

Details zu ATF3

Target: ATF3 (Activating Transcription Factor 3 (ATF3))

Andere Bezeichnung: ATF3

Hintergrund:

Target Description: Activating transcription factor 3 is a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. Multiple transcript variants encoding two different isoforms have been found for this gene. The longer isoform represses rather than activates transcription from promoters with ATF binding elements. The shorter isoform (deltaZip2) lacks the leucine zipper protein-dimerization motif and does not bind to DNA, and it stimulates transcription presumably by sequestering inhibitory co-factors away from the promoter. It is possible that alternative splicing of the ATF3 gene may be physiologically important in the regulation of target genes.

Gene Symbol: ATF3

Molekulargewicht: 20576 Da

Gen-ID: 467

UniProt: P18847

Pathways: Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Unfolded Protein Response