ATF3 Antikörper

Produktnummer ABIN5676162

Dieser Maus Monoklonal Antikörper detektiert spezifisch ATF3 in ICC und DB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für ATF3 Antikörper (ABIN5676162)

Target: ATF3 (Activating Transcription Factor 3 (ATF3))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ATF3 Antikörper ist unkonjugiert

Applikation: Immunocytochemistry (ICC), Dot Blot (DB)

Klon: 44C3a

Produktdetails anti-ATF3 Antikörper

Kreuzreaktivität: Human

Kreuzreaktivität (Details): Other species not studied.

Aufreinigung: Protein G affinity chromatography

Immunogen: ATF3 antibody was raised in mouse using recombinant Human Activating Transcription Factor 3

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ICC: 2-100 µg/mL
Optimal conditions should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: Lot specific

Buffer: ATF3 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Details zu ATF3

Target: ATF3 (Activating Transcription Factor 3 (ATF3))

Andere Bezeichnung: ATF3

Hintergrund: Activating transcription factor 3 is a member of the mammalian activation transcription factor/cAMP responsive elementbinding (CREB) protein family of transcription factors. Multiple transcript variants encoding two different isoforms have been found for this gene. The longer isoform represses rather than activates transcription from promoters with ATF binding elements. The shorter isoform (deltaZip2) lacks the leucine zipper protein-dimerization motif and does not bind to DNA, and it stimulates transcription presumably by sequestering inhibitory co-factors away from the promoter. Synonyms: Monoclonal ATF3 antibody, Anti-ATF3 antibody, Cyclic AMP-dependent transcription factor ATF-3 antibody.

Pathways: Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Unfolded Protein Response