TLR2 Antikörper (N-Term)

Produktnummer ABIN2798860

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch TLR2 in WB, IHC und FACS. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für TLR2 Antikörper (N-Term) (ABIN2798860)

Target: TLR2 (Toll-Like Receptor 2 (TLR2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TLR2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Produktdetails anti-TLR2 Antikörper

Bindungsspezifität: AA 212-242, N-Term

Verwendungszweck: Rabbit Anti-Human TLR2 (N-term) Antibody

Immunogen: This TLR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 212-242 amino acids from the N-terminal region of human TLR2.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Western Blot, Immunohistochemistry, Flow Cytometry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50, FC: 1:10-50Western blot analysis of hTLR2-C226 . FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 2.0 mg/mL

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C (short-term), -20°C (long-term)

Details zu TLR2

Target: TLR2 (Toll-Like Receptor 2 (TLR2))

Andere Bezeichnung: TLR2

Hintergrund:

Target Description: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB.

Gene Symbol: TLR2

Molekulargewicht: 89838 Da

Gen-ID: 7097

UniProt: O60603

Pathways: TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades