SOCS6 Antikörper (N-Term)

Produktnummer ABIN2798439

Dieses Anti-SOCS6-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SOCS6 in WB und IHC. Geeignet für Human.

Kurzübersicht für SOCS6 Antikörper (N-Term) (ABIN2798439)

Target: SOCS6 (Suppressor of Cytokine Signaling 6 (SOCS6))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SOCS6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-SOCS6 Antikörper

Bindungsspezifität: AA 40-69, N-Term

Verwendungszweck: Rabbit Anti-Human SOCS6 (N-term) Antibody

Immunogen: This SOCS6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-69 amino acids from the N-terminal region of human SOCS6.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50SOCS6 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C (short-term), -20°C (long-term)

Details zu SOCS6

Target: SOCS6 (Suppressor of Cytokine Signaling 6 (SOCS6))

Andere Bezeichnung: SOCS6

Hintergrund:

Target Description: The protein encoded by this gene contains a SH2 domain and a CIS homolog domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by GM-CSF and EPO in hematopoietic cells. A high expression level of this gene was found in factor-independent chronic myelogenous leukemia (CML) and erythroleukemia (HEL) cell lines.

Gene Symbol: SOCS6

Molekulargewicht: 59528 Da

Gen-ID: 9306

UniProt: O14544

Pathways: JAK-STAT Signalweg, Carbohydrate Homeostasis