IRF9 Antikörper (N-Term)
Kurzübersicht für IRF9 Antikörper (N-Term) (ABIN2797511)
Target
Alle IRF9 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 75-104, N-Term
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Verwendungszweck
- Rabbit Anti-Mouse IRF9 (N-term) Antibody
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Immunogen
- This IRF9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 75-104 amino acids from the N-terminal region of human IRF9.
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Isotyp
- Ig Fraction
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Applikationshinweise
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Western Blot, Immunohistochemistry, Immunofluorescence
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50, IF: 1:10-50IRF9 Antibody (N-term) . -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.280 mg/mL
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- 2-8°C (short-term), -20°C (long-term)
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- IRF9 (Interferon Regulatory Factor 9 (IRF9))
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Andere Bezeichnung
- IRF9
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Hintergrund
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Target Description: IRF9 is a transcription regulatory factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.
Gene Symbol: IRF9
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Molekulargewicht
- 43696 Da
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Gen-ID
- 10379
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UniProt
- Q00978
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Pathways
- JAK-STAT Signalweg, Interferon-gamma Pathway, Hepatitis C
Target
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