FZD7 Antikörper (Center)
Kurzübersicht für FZD7 Antikörper (Center) (ABIN2795184)
Target
Alle FZD7 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 202-229, Center
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Verwendungszweck
- Rabbit Anti-Human FZD7 (Center) Antibody
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Immunogen
- This FZD7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 202-229 amino acids from the Central region of human FZD7.
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Isotyp
- Ig Fraction
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Applikationshinweise
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Western Blot
Recommended Dilutions
WB: 1:1000FZD7 Antibody (Center) . -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 mg/mL
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- 2-8°C (short-term), -20°C (long-term)
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- FZD7 (Frizzled Family Receptor 7 (FZD7))
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Andere Bezeichnung
- FZD7
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Hintergrund
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Target Description: Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas.
Gene Symbol: FZD7
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Molekulargewicht
- 63620 Da
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Gen-ID
- 8324
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UniProt
- O75084
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Pathways
- WNT Signalweg, Stem Cell Maintenance
Target
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