PDK4 Antikörper (AA 250-277)
Kurzübersicht für PDK4 Antikörper (AA 250-277) (ABIN2795139)
Target
Alle PDK4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 250-277
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Verwendungszweck
- Rabbit Anti-Human PDK4 (E265) Antibody
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Immunogen
- This PDK4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 250-277 amino acids from human PDK4.
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Isotyp
- Ig Fraction
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Applikationshinweise
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Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50Western blot analysis of PDK4 Antibody (E265) in CEM cell line lysates (35 μg/lane). PDK4 (arrow) was detected using the purified Pab.
Formalin-fixed and paraffin-embedded human skeletal muscle tissue reacted with PDK4-E265, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry, clinical relevance has not been evaluated. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 mg/mL
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- 2-8°C (short-term), -20°C (long-term)
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- PDK4 (Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4))
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Andere Bezeichnung
- PDK4
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Hintergrund
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Target Description: PDK4 inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.
Gene Symbol: PDK4
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Molekulargewicht
- 46469 Da
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Gen-ID
- 5166
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UniProt
- Q16654
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Pathways
- PI3K-Akt Signalweg, Hedgehog Signalweg, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effekt
Target
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