IGF1 Antikörper (N-Term)

Produktnummer ABIN2793143

Der Kaninchen Polyklonal Anti-IGF1-Antikörper wurde für WB, IHC, IF und FACS validiert. Er ist geeignet, IGF1 in Proben von Human zu detektieren.

Kurzübersicht für IGF1 Antikörper (N-Term) (ABIN2793143)

Target: IGF1 (Insulin-Like Growth Factor 1 (IGF1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IGF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Produktdetails anti-IGF1 Antikörper

Bindungsspezifität: AA 51-77, N-Term

Verwendungszweck: Rabbit Anti-Human IGF1R (N-term K66) Antibody

Immunogen: This IGF1R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-77 amino acids from the N-terminal region of human IGF1R.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Western Blot, Immunohistochemistry, Flow Cytometry, Immunofluorescence
Recommended Dilutions
WB: 1:1000, IHC: 1:50-100, FC: 1:10-50, IF: 1:10-50Western blot analysis of IGF1R Antibody (N-term K66) .

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 2.000 mg/mL

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C (short-term), -20°C (long-term)

Details zu IGF1

Target: IGF1 (Insulin-Like Growth Factor 1 (IGF1))

Andere Bezeichnung: IGF1

Hintergrund:

Target Description: The IGF1R receptor binds insulin-like growth factor with a high affinity and plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. The protein possess tyrosine kinase activity.

Gene Symbol: IGF1R

Molekulargewicht: 154793 Da

Gen-ID: 3480

UniProt: P08069

Pathways: RTK Signalweg, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Hormone Activity, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Stem Cell Maintenance, Glycosaminoglycan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Autophagie, Smooth Muscle Cell Migration, Activated T Cell Proliferation, Positive Regulation of fat Cell Differentiation