GLI1 Antikörper (N-Term)

Produktnummer ABIN2792532

Der Kaninchen Polyklonal Anti-GLI1-Antikörper wurde für WB validiert. Er ist geeignet, GLI1 in Proben von Human, Hund, Meerschweinchen, Pferd, Kaninchen und Rind (Kuh) zu detektieren.

Kurzübersicht für GLI1 Antikörper (N-Term) (ABIN2792532)

Target: GLI1 (Zinc Finger Protein GLI1 (GLI1))

Reaktivität: Human, Hund, Meerschweinchen, Pferd, Kaninchen, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GLI1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GLI1 Antikörper

Bindungsspezifität: N-Term

Sequenz: LRPLPSQGAP SVGTEGLSGP PFCHQANLMS GPHSYGPARE TNSCTEGPLF

Kreuzreaktivität: Rind (Kuh), Hund, Human

Homologie: Cow: 92%, Dog: 92%, Guinea Pig: 85%, Horse: 100%, Human: 100%, Rabbit: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against GLI1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GLI1

Anwendungsinformationen

Applikationshinweise: WB Suggested Anti-GLI1 Antibody Titration: 1.25 µg/mL
ELISA Titer: 1:62500
Positive Control: Jurkat cell lysate.
Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1106 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu GLI1

Target: GLI1 (Zinc Finger Protein GLI1 (GLI1))

Andere Bezeichnung: GLI1

Hintergrund: GLI1 is a protein which is a member of the Kruppel family of zinc finger proteins. The function of this gene has not been determined, however, it may play a role in normal development gene transcription. Mouse mutation studies indicate possible involvement in human foregut malformation.
Alias Symbols: GLI
Protein Interaction Partner: TRIM42, GCC1, PRKAA2, VHL, FEM1B, CDK4, UBC, MYC, ITCH, NUMB, SUFU, RAI1, XBP1, HDAC2, HDAC1, STK36, DYRK1A, ZIC2, ZIC1, Sin3a, Shh, SAP18, Su(fu), Pias1,
Protein Size: 1106

Molekulargewicht: 118 kDa

Gen-ID: 2735

NCBI Accession: NM_005269, NP_005260

UniProt: P08151

Pathways: Hedgehog Signalweg, Dopaminergic Neurogenesis