E2F1 Antikörper (C-Term)
Kurzübersicht für E2F1 Antikörper (C-Term) (ABIN2792180)
Target
Alle E2F1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- C-Term
-
Verwendungszweck
- E2F1 Antibody - C-terminal region
-
Sequenz
- REDFSGLLPE EFISLSPPHE ALDYHFGLEE GEGIRDLFDC DFGDLTPLDF
-
Homologie
- Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
-
Produktmerkmale
- This is a rabbit polyclonal antibody against E2F1. It was validated on Western Blot using a cell lysate as a positive control.
-
Aufreinigung
- Affinity Purified
-
Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human E2F1
-
-
-
-
Applikationshinweise
- Optimal working dilution should be determined by the investigator.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 0.5 mg/mL
-
Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Handhabung
- prevent freeze-thaw cycles
-
Lagerung
- 4 °C,-20 °C
-
Informationen zur Lagerung
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
-
-
- E2F1 (E2F Transcription Factor 1 (E2F1))
-
Andere Bezeichnung
- E2F1
-
Hintergrund
-
Background Information: The protein encoded by E2F1 is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent/independent apoptosis.
Gene Name: E2F transcription factor 1
Alternative Symbols: RBP3, E2F-1, RBAP1, RBBP3
Protein Name: Transcription factor E2F1
-
Molekulargewicht
- 47kDa
-
Gen-ID
- 1869
-
NCBI Accession
- NP_005216
-
UniProt
- Q01094
-
Pathways
- p53 Signalweg, Zellzyklus, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Autophagie
Target
-