Ephrin A5 Antikörper (N-Term)

Produktnummer ABIN2790146

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Ephrin A5 in WB. Er zeigt eine Reaktivität gegenüber Human, Ratte, Maus, Rind (Kuh), Kaninchen, Hund, Pferd, Meerschweinchen, Zebrafisch (Danio rerio) und Saccharomyces cerevisiae.

Kurzübersicht für Ephrin A5 Antikörper (N-Term) (ABIN2790146)

Target: Ephrin A5 (EFNA5)

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Kaninchen, Hund, Pferd, Meerschweinchen, Zebrafisch (Danio rerio), Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Ephrin A5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Ephrin A5 Antikörper

Bindungsspezifität: N-Term

Sequenz: EDSVPEDKTE RYVLYMVNFD GYSACDHTSK GFKRWECNRP HSPNGPLKFS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against EFNA5. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human EFNA5

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 228 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Ephrin A5

Target: Ephrin A5 (EFNA5)

Andere Bezeichnung: EFNA5

Hintergrund: Ephrin-A5, a member of the ephrin gene family, prevents axon bundling in cocultures of cortical neurons with astrocytes, a model of late stage nervous system development and differentiation. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system. EPH receptors typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin ligands and receptors have been named by the Eph Nomenclature Committee (1997). Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are similarly divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.
Alias Symbols: AF1, EFL5, EPLG7, GLC1M, LERK7, RAGS
Protein Interaction Partner: MYC, GRIP1, SRC, EPHA7, EPHA4, EPHB2, EPHB1, EPHA5, EPHA3, EPHA2, EPHA8,
Protein Size: 228

Molekulargewicht: 24 kDa

Gen-ID: 1946

NCBI Accession: NM_001962, NP_001953

UniProt: P52803

Pathways: RTK Signalweg