Exonuclease 1 Antikörper (N-Term)

Produktnummer ABIN2789520

Produktdetails anti-Exonuclease 1 Antikörper

Target: Exonuclease 1 (EXO1)

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Meerschweinchen, Kaninchen, Rind (Kuh), Hund, Zebrafisch (Danio rerio), Pferd, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Exonuclease 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: ILVFDGCTLP SKKEVERSRR ERRQANLLKG KQLLREGKVS EARECFTRSI

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 79%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against EXO1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 803 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Exonuclease 1

Target: Exonuclease 1 (EXO1)

Andere Bezeichnung: EXO1 (EXO1 Produkte)

Synonyme: HEX1 antikoerper, hExoI antikoerper, 5730442G03Rik antikoerper, Msa antikoerper, EXO1 antikoerper, exoi antikoerper, fc16e04 antikoerper, wu:fc16e04 antikoerper, zgc:55521 antikoerper, exonuclease 1 antikoerper, hypothetical protein antikoerper, exonuclease I Exo1 antikoerper, RNA exonuclease antikoerper, exonuclease 1 S homeolog antikoerper, EXO1 antikoerper, Y17G7B.12 antikoerper, SJAG_01832 antikoerper, PAS_chr1-1_0377 antikoerper, Exo1 antikoerper, exo1 antikoerper, exo1.S antikoerper, LOC100338764 antikoerper

Hintergrund: This gene encodes a protein with 5' to 3' exonuclease activity as well as an RNase H activity. It is similar to the Saccharomyces cerevisiae protein Exo1 which interacts with Msh2 and which is involved in mismatch repair and recombination. Alternative splicing of this gene results in three transcript variants encoding two different isoforms.
Alias Symbols: HEX1, hExoI
Protein Interaction Partner: YWHAB, MLH1, PCNA, UBC, SUMO2, YWHAQ, YWHAZ, YWHAH, YWHAG, YWHAE, MSH2, KPNA4, KPNB1, SFN, ATM, PMS2, PMS1, BLM, MSH3,
Protein Size: 803

Molekulargewicht: 89 kDa

Gen-ID: 9156

NCBI Accession: NM_003686, NP_003677

UniProt: Q9UQ84

Pathways: DNA Reparatur, Production of Molecular Mediator of Immune Response