Exonuclease 1 Antikörper (AA 301-600)

Produktnummer ABIN7152265

Produktdetails anti-Exonuclease 1 Antikörper

Target: Exonuclease 1 (EXO1)

Bindungsspezifität: AA 301-600

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Exonuclease 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Exonuclease 1 protein (301-600AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu Exonuclease 1

Target: Exonuclease 1 (EXO1)

Andere Bezeichnung: EXO1 (EXO1 Produkte)

Synonyme: HEX1 antikoerper, hExoI antikoerper, 5730442G03Rik antikoerper, Msa antikoerper, EXO1 antikoerper, exoi antikoerper, fc16e04 antikoerper, wu:fc16e04 antikoerper, zgc:55521 antikoerper, exonuclease 1 antikoerper, hypothetical protein antikoerper, exonuclease I Exo1 antikoerper, RNA exonuclease antikoerper, exonuclease 1 S homeolog antikoerper, EXO1 antikoerper, Y17G7B.12 antikoerper, SJAG_01832 antikoerper, PAS_chr1-1_0377 antikoerper, Exo1 antikoerper, exo1 antikoerper, exo1.S antikoerper, LOC100338764 antikoerper

Hintergrund:

Background: 5\'->3\' double-stranded DNA exonuclease which may also possess a cryptic 3\'->5\' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair (MMR) to excise mismatch-containing DNA tracts directed by strand breaks located either 5\' or 3\' to the mismatch. Also exhibits endonuclease activity against 5\'-overhanging flap structures similar to those generated by displacement synthesis when DNA polymerase encounters the 5\'-end of a downstream Okazaki fragment. Required for somatic hypermutation (SHM) and class switch recombination (CSR) of immunoglobulin genes. Essential for male and female meiosis.

Aliases: exo1 antibody, EXO1_HUMAN antibody, ExoI antibody, Exonuclease 1 antibody, Exonuclease I antibody, Exonuclease1 antibody, HEX1 antibody, hExo I antibody, hExo1 antibody, hExoI antibody, Rad2 nuclease family member homolog of S. cerevisiae exonuclease 1 antibody

UniProt: Q9UQ84

Pathways: DNA Reparatur, Production of Molecular Mediator of Immune Response