SPHK1 Antikörper (Middle Region)

Produktnummer ABIN2789510

Dieses Anti-SPHK1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SPHK1 in WB. Geeignet für Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Ziege und Kaninchen.

Kurzübersicht für SPHK1 Antikörper (Middle Region) (ABIN2789510)

Target: SPHK1 (Sphingosine Kinase 1 (SPHK1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Ziege, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPHK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SPHK1 Antikörper

Bindungsspezifität: Middle Region

Sequenz: DVDLESEKYR RLGEMRFTLG TFLRLAALRT YRGRLAYLPV GRVGSKTPAS

Homologie: Cow: 93%, Dog: 93%, Goat: 77%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against SPHK1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 384 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SPHK1

Target: SPHK1 (Sphingosine Kinase 1 (SPHK1))

Andere Bezeichnung: SPHK1

Hintergrund: The protein encoded by this gene catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P), a lipid mediator with both intra- and extracellular functions. Intracellularly, S1P regulates proliferation and survival, and extracellularly, it is a ligand for cell surface G protein-coupled receptors. This protein, and its product S1P, play a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: SPHK
Protein Interaction Partner: UBC, BIRC3, MBTPS1, TRAF6, RARG, EP300, SPHKAP, RPS6KC1, CTNND2, TRAF2, LYN, FYN, CTSB,
Protein Size: 384

Molekulargewicht: 42 kDa

Gen-ID: 8877

NCBI Accession: NM_001142601, NP_001136073

UniProt: Q9NYA1

Pathways: VEGF Signaling