SPHK1 Antikörper (AA 313-343)
Kurzübersicht für SPHK1 Antikörper (AA 313-343) (ABIN3032708)
Target
Alle SPHK1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 313-343
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Verwendungszweck
- SPHK1 Antibody
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Aufreinigung
- Purified
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Immunogen
- A portion of amino acids 313-343 from the human protein was used as the immunogen for this SPHK1 antibody.
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Isotyp
- Ig Fraction
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anti-Sphingosine Kinase 1 (SPHK1) (AA 1-384) antibody
SPHK1 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 1D6 unconjugated
anti-Sphingosine Kinase 1 (SPHK1) (AA 286-315) antibodySPHK1 Reaktivität: Human, Maus, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal RB03621 unconjugated
anti-Sphingosine Kinase 1 (SPHK1) (AA 1-30), (N-Term) antibodySPHK1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB3619 unconjugated
anti-Sphingosine Kinase 1 (SPHK1) (AA 286-315) antibodySPHK1 Reaktivität: Human, Maus, Ratte, Primate WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Sphingosine Kinase 1 (SPHK1) (AA 148-398) antibodySPHK1 Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Sphingosine Kinase 1 (SPHK1) (AA 1-384) antibodySPHK1 Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Sphingosine Kinase 1 (SPHK1) (AA 50-384) antibodySPHK1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Sphingosine Kinase 1 (SPHK1) (AA 59-89), (N-Term) antibodySPHK1 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB15394 unconjugated
anti-Sphingosine Kinase 1 (SPHK1) (AA 313-343), (C-Term) antibodySPHK1 Reaktivität: Human WB, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB15395 unconjugated
anti-Sphingosine Kinase 1 (SPHK1) (AA 1-30) antibodySPHK1 Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- Titration of the SPHK1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the SPHK1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- SPHK1 (Sphingosine Kinase 1 (SPHK1))
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Andere Bezeichnung
- SPHK1
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Hintergrund
- SPHK1 is a novel lipid messenger with both intracellular and extracellular functions. Intracellularly, it regulates proliferation and survival, and extracellularly, it is a ligand for EDG1 (MIM 601974). Various stimuli increase cellular levels of SPP by activation of sphingosine kinase (SPHK), the enzyme that catalyzes the phosphorylation of sphingosine. Competitive inhibitors of SPHK block formation of SPP and selectively inhibit cellular proliferation induced by a variety of factors, including platelet-derived growth factor (e.g., MIM 173430) and serum.
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UniProt
- Q9NYA1
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Pathways
- VEGF Signaling
Target
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