ROCK2 Antikörper (Middle Region)

Produktnummer ABIN2788813

Der Kaninchen Polyklonal anti-ROCK2 Antikörper (ABIN2788813) detektiert spezifisch ROCK2 in WB und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Schwein, Kaninchen, Meerschweinchen und Zebrafisch (Danio rerio).

Kurzübersicht für ROCK2 Antikörper (Middle Region) (ABIN2788813)

Target: ROCK2 (rho-Associated, Coiled-Coil Containing Protein Kinase 2 (ROCK2))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Schwein, Kaninchen, Meerschweinchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ROCK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-ROCK2 Antikörper

Bindungsspezifität: Middle Region

Sequenz: KNAEYQRKAD HEADKKRNLE NDVNSLKDQL EDLKKRNQNS QISTEKVNQL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 79%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against ROCK2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1388 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ROCK2

Target: ROCK2 (rho-Associated, Coiled-Coil Containing Protein Kinase 2 (ROCK2))

Andere Bezeichnung: ROCK2

Hintergrund: The protein encoded by this gene is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho.
Alias Symbols: KIAA0619, ROCK-II
Protein Interaction Partner: UBC, FAM21A, RABGEF1, GPHN, KIAA0196, MTA2, ZW10, NHP2L1, LMNA, MAGEC1, ELAVL1, PPP1R12A, STAU1, RHOA, IKBKE, STK16, MBP,
Protein Size: 1388

Molekulargewicht: 153 kDa

Gen-ID: 9475

NCBI Accession: NM_004850, NP_004841

UniProt: O75116

Pathways: Microtubule Dynamics, WNT Signalweg, Tube Formation