H2AFZ Antikörper (N-Term)

Produktnummer ABIN2788776

Produktdetails anti-H2AFZ Antikörper

Target: H2AFZ (H2A Histone Family, Member Z (H2AFZ))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Schaf, Rind (Kuh), Zebrafisch (Danio rerio), Hund, Meerschweinchen, Kaninchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser H2AFZ Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: AGGKAGKDSG KAKTKAVSRS QRAGLQFPVG RIHRHLKSRT TSHGRVGATA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against H2AFZ. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 128 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu H2AFZ

Target: H2AFZ (H2A Histone Family, Member Z (H2AFZ))

Andere Bezeichnung: H2AFZ (H2AFZ Produkte)

Synonyme: H2A.Z-1 antikoerper, H2A.z antikoerper, H2A/z antikoerper, H2AZ antikoerper, H2A.Z antikoerper, H2a.z-1 antikoerper, H2AFV antikoerper, H2Az antikoerper, XH2AZ antikoerper, h2a.zl1 antikoerper, h2a.zl2 antikoerper, H2A histone family member Z antikoerper, H2A histone family, member Z antikoerper, H2A histone family member Z L homeolog antikoerper, histone H2A.Z antikoerper, H2AFZ antikoerper, H2afz antikoerper, h2afz.L antikoerper

Hintergrund: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality.
Alias Symbols: H2A.z, H2A/z, H2AZ, MGC117173
Protein Interaction Partner: UBC, ASB9, ASB16, WWOX, ZBTB1, OGFOD1, TRNT1, ACAA2, NOL3, EZR, PYGL, PSMD9, FH, UBD, PAN2, HIST1H3B, CENPA, MAGEC1, SUMO1, SUMO3, NEDD8, EPC1, MEAF6, ACTR6, EP400, DMAP1, MRGBP, ING3, MORF4L1, RUVBL2, SRCAP, KAT5, RUVBL1, TRRAP, YEATS4, VPS72, ACTL6A, HI
Protein Size: 128

Molekulargewicht: 14 kDa

Gen-ID: 3015

NCBI Accession: NM_002106, NP_002097

UniProt: P0C0S5

Pathways: Telomere Maintenance