TNFAIP3 Antikörper (C-Term)

Produktnummer ABIN2788768

Produktdetails anti-TNFAIP3 Antikörper

Target: TNFAIP3 (Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3))

Bindungsspezifität: C-Term

Reaktivität: Human, Ratte, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TNFAIP3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: QENSEQGRRE GHAQNPMEPS VPQLSLMDVK CETPNCPFFM SVNTQPLCHE

Homologie: Dog: 79%, Human: 100%, Rat: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against TNFAIP3. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of human TNFAIP3

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TNFAIP3

Target: TNFAIP3 (Tumor Necrosis Factor, alpha-Induced Protein 3 (TNFAIP3))

Andere Bezeichnung: TNFAIP3 (TNFAIP3 Produkte)

Hintergrund: This gene was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). The protein encoded by this gene is a zinc finger protein and ubiqitin-editing enzyme, and has been shown to inhibit NF-kappa B activation as well as TNF-mediated apoptosis. The encoded protein, which has both ubiquitin ligase and deubiquitinase activities, is involved in the cytokine-mediated immune and inflammatory responses. Several transcript variants encoding the same protein have been found for this gene.
Alias Symbols: A20, AISBL, OTUD7C, TNFA1P2
Protein Size: 471

Molekulargewicht: 51 kDa

Gen-ID: 7128

NCBI Accession: NM_001270507, NP_001257436

UniProt: P21580

Pathways: TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Production of Molecular Mediator of Immune Response