OGG1 Antikörper (C-Term)

Produktnummer ABIN2788728

Dieser Anti-OGG1 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von OGG1 in WB. Geeignet für Human, Maus, Ratte, Hund, Pferd, Rind (Kuh) und Schwein.

Kurzübersicht für OGG1 Antikörper (C-Term) (ABIN2788728)

Target: OGG1 (8-Oxoguanine DNA Glycosylase (OGG1))

Reaktivität: Human, Maus, Ratte, Hund, Pferd, Rind (Kuh), Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser OGG1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-OGG1 Antikörper

Bindungsspezifität: C-Term

Sequenz: AVPVDVHMWH IAQRDYSWHP TTSQAKGPSP QTNKELGNFF RSLWGPYAGW

Spezifität: Directed against isoforms 2D, 1A, 1B, 2E.

Homologie: Cow: 93%, Dog: 100%, Horse: 86%, Human: 100%, Mouse: 86%, Pig: 92%, Rat: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against OGG1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 345 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu OGG1

Target: OGG1 (8-Oxoguanine DNA Glycosylase (OGG1))

Andere Bezeichnung: OGG1

Hintergrund: This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization.
Alias Symbols: HMMH, HOGG1, MUTM, OGH1
Protein Interaction Partner: ERCC6, ERCC8, UBC, Ogg1, CHGB, XRCC1, PRKCA, SNRPF,
Protein Size: 345

Molekulargewicht: 38 kDa

Gen-ID: 4968

NCBI Accession: NM_016829, NP_058438

UniProt: O15527

Pathways: DNA Reparatur