IL-18 Antikörper (C-Term)
-
- Target Alle IL-18 (IL18) Antikörper anzeigen
- IL-18 (IL18) (Interleukin 18 (IL18))
-
Bindungsspezifität
- C-Term
-
Reaktivität
- Human, Maus, Ratte
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser IL-18 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB)
- Sequenz
- IIFFQRSVPG HDNKMQFESS SYEGYFLACE KERDLFKLIL KKEDELGDRS
- Homologie
- Human: 100%, Mouse: 79%, Rat: 79%
- Produktmerkmale
- This is a rabbit polyclonal antibody against IL18. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human IL18
- Top Product
- Discover our top product IL18 Primärantikörper
-
-
- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
-
Antigen size: 193 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Target
- IL-18 (IL18) (Interleukin 18 (IL18))
- Andere Bezeichnung
- IL18 (IL18 Produkte)
- Synonyme
- Igif antikoerper, Il-18 antikoerper, IL-18 antikoerper, IGIF antikoerper, ChIL-18 antikoerper, IL-1g antikoerper, IL1F4 antikoerper, IL18 antikoerper, interleukin 18 antikoerper, Il18 antikoerper, IL18 antikoerper
- Hintergrund
-
The protein encoded by this gene is a proinflammatory cytokine. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL-18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity.
Alias Symbols: IGIF, IL-18, IL-1g, IL1F4, MGC12320
Protein Interaction Partner: CASK, UBC, IL1RL2, IL18RAP, IL18R1, IL18BP, CASP4, CASP3, CASP1,
Protein Size: 193 - Molekulargewicht
- 18 kDa
- Gen-ID
- 3606
- NCBI Accession
- NM_001562, NP_001553
- UniProt
- Q14116
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Activated T Cell Proliferation, Cancer Immune Checkpoints, Inflammasome
-