Calnexin Antikörper (Middle Region)

Produktnummer ABIN2788199

Produktdetails anti-Calnexin Antikörper

Target: Calnexin (CANX)

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Kaninchen, Meerschweinchen, Pferd, Ziege, Zebrafisch (Danio rerio), Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Calnexin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: LVDQSVVNSG NLLNDMTPPV NPSREIEDPE DRKPEDWDER PKIPDPEAVK

Homologie: Cow: 100%, Dog: 93%, Goat: 79%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 80%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against CANX. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CANX

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 592 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Calnexin

Target: Calnexin (CANX)

Andere Bezeichnung: CANX (CANX Produkte)

Synonyme: CNX antikoerper, IP90 antikoerper, P90 antikoerper, 1110069N15Rik antikoerper, AI988026 antikoerper, Cnx antikoerper, D11Ertd153e antikoerper, canx antikoerper, clgn antikoerper, clnx antikoerper, cnx antikoerper, PP90 antikoerper, zgc:63524 antikoerper, wu:fe06b12 antikoerper, CANX antikoerper, calnexin antikoerper, CalNeXin antikoerper, calnexin L homeolog antikoerper, CANX antikoerper, Canx antikoerper, cnx-1 antikoerper, canx.L antikoerper, canx antikoerper, LOC100283947 antikoerper

Hintergrund: This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding the same protein have been described.
Alias Symbols: CNX, FLJ26570, IP90, P90
Protein Interaction Partner: ERLIN2, HUWE1, UBC, TRAF6, SUMO2, TOR1A, STAU1, MDM2, LGR4, WWOX, NPHS1, RPA3, RPA2, RPA1, SUZ12, RNF2, BMI1, FBXO6, PTGIR, ADRB2, PDIA3, CLN5, YIPF3, SMURF2, env, PGRMC1, BCAP31, UBL4A, SERPINA1, MTNR1A, CSNK2A1, ATF2, CFTR, VCP, PKD2, LDLR, ASGR1, KCNH2
Protein Size: 592

Molekulargewicht: 65 kDa

Gen-ID: 821

NCBI Accession: NM_001746, NP_001737

UniProt: P27824

Pathways: MAPK Signalweg, Thyroid Hormone Synthesis