ATG5 Antikörper (Middle Region)

Produktnummer ABIN2787927

Dieses Anti-ATG5-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ATG5 in WB. Geeignet für Human, Maus, Ratte, Zebrafisch (Danio rerio), Rind (Kuh), Kaninchen, Meerschweinchen, Pferd, Hund und Schaf.

Kurzübersicht für ATG5 Antikörper (Middle Region) (ABIN2787927)

Target: ATG5 (ATG5 Autophagy Related 5 (ATG5))

Reaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio), Rind (Kuh), Kaninchen, Meerschweinchen, Pferd, Hund, Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATG5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ATG5 Antikörper

Bindungsspezifität: Middle Region

Sequenz: RFDQFWAINR KLMEYPAEEN GFRYIPFRIY QTTTERPFIQ KLFRPVAADG

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against ATG5. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ATG5

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 275 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ATG5

Target: ATG5 (ATG5 Autophagy Related 5 (ATG5))

Andere Bezeichnung: ATG5

Hintergrund: ATG5 is required for autophagy. It conjugates to ATG12 and associates with isolation membrane to form cup-shaped isolation membrane and autophagosome. The conjugate detaches from the membrane immediately before or after autophagosome formation is completed. ATG5 may play an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity.
Alias Symbols: APG5, APG5-LIKE, APG5L, ASP, hAPG5
Protein Interaction Partner: TEKT4, CCHCR1, WIPI2, KEAP1, VCP, MEOX2, FADD, ATG16L1, RB1CC1, EXOC4, ATG3, ATG12, CAV1, HTT, WDFY3, TAB3, TAB2, TECPR1, ELAVL1, UBC, SIRT1, TKT, MAP1LC3C, MAP1LC3B, ATG10, ATG5, IMPDH2,
Protein Size: 275

Molekulargewicht: 32 kDa

Gen-ID: 9474

NCBI Accession: NM_004849, NP_004840

UniProt: Q9H1Y0

Pathways: Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Autophagie