CDK1 Antikörper (Middle Region)

Produktnummer ABIN2787664

Der Kaninchen Polyklonal Anti-CDK1-Antikörper wurde für WB validiert. Er ist geeignet, CDK1 in Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Schaf, Kaninchen, Zebrafisch (Danio rerio), Meerschweinchen, Ziege und Pferd zu detektieren.

Kurzübersicht für CDK1 Antikörper (Middle Region) (ABIN2787664)

Target: CDK1 (Cyclin-Dependent Kinase 1 (CDK1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Schaf, Kaninchen, Zebrafisch (Danio rerio), Meerschweinchen, Ziege, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CDK1 Antikörper

Bindungsspezifität: Middle Region

Sequenz: DYKNTFPKWK PGSLASHVKN LDENGLDLLS KMLIYDPAKR ISGKMALNHP

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 83%

Produktmerkmale: This is a rabbit polyclonal antibody against CDC2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CDC2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 240 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CDK1

Target: CDK1 (Cyclin-Dependent Kinase 1 (CDK1))

Andere Bezeichnung: CDC2

Hintergrund: The protein encoded by CDC2 is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control.
Alias Symbols: CDC28A, CDK1, DKFZp686L20222, MGC111195, CDC2, P34CDC2
Protein Interaction Partner: ABL1, SIRT1, CDC37, HUWE1, BTRC, UBC, HSP90AA1, HSPA4, HIST1H1A, GADD45A, CKS1B, USP16, Samhd1, UIMC1, SUMO2, CCNA2, STAU1, RNF2, CKS2, ZRANB2, CDKN1B, CDKN1A, CDK1, CCNB1, FBXO6, CCNB2, PKMYT1, SQSTM1, EGFR, PTMA, DCTN6, RGCC, BAG3, CDC25B, BCL2, TP53BP1
Protein Size: 240

Molekulargewicht: 27 kDa

Gen-ID: 983

NCBI Accession: NM_033379, NP_203698

UniProt: P06493

Pathways: Zellzyklus, Fc-epsilon Rezeptor Signalübertragung, Neurotrophin Signalübertragung, Activation of Innate immune Response, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Toll-Like Receptors Cascades, Synthesis of DNA