MAPK7 Antikörper (Middle Region)

Produktnummer ABIN2787362

Dieses Anti-MAPK7-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von MAPK7 in WB und IHC. Geeignet für Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Meerschweinchen und Pferd.

Kurzübersicht für MAPK7 Antikörper (Middle Region) (ABIN2787362)

Target: MAPK7 (Mitogen-Activated Protein Kinase 7 (MAPK7))

Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAPK7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-MAPK7 Antikörper

Bindungsspezifität: Middle Region

Sequenz: FDMGVADGPQ DGQADSASLS ASLLADWLEG HGMNPADIES LQREIQMDSP

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against MAPK7. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MAPK7

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 816 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MAPK7

Target: MAPK7 (Mitogen-Activated Protein Kinase 7 (MAPK7))

Andere Bezeichnung: MAPK7

Hintergrund: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5). It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported.
Alias Symbols: BMK1, ERK4, ERK5, PRKM7
Protein Interaction Partner: PRKCZ, NFE2L2, UBE2C, MAP3K2, TP53, MAP2K5, PML, DSG1, DSC1, PFDN6, VBP1, MAPK7, PFDN5, PFDN4, PFDN2, PFDN1, JUP, GAPDH, BAG3, PKM, LDHC, HSP90AB1, HSPA5, HSPA4, ATP5A1, ACTB, PPP3CA, TUBB, MYLK2, GANAB, CDC37, YWHAZ, YWHAH, YWHAG, YWHAE, UBC, HSP90B1, FS
Protein Size: 816

Molekulargewicht: 88 kDa

Gen-ID: 5598

NCBI Accession: NM_139034, NP_620603

UniProt: Q13164

Pathways: MAPK Signalweg, Neurotrophin Signalübertragung, Activation of Innate immune Response, cAMP Metabolic Process, Toll-Like Receptors Cascades, Negative Regulation of intrinsic apoptotic Signaling