MAPK7 Antikörper
Kurzübersicht für MAPK7 Antikörper (ABIN5557449)
Target
Alle MAPK7 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Kreuzreaktivität
- Human, Maus, Ratte
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Aufreinigung
- Purified by Protein A.
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Immunogen
- Recombinant human ERK5 protein, around C-terminal 200aa.
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Isotyp
- IgG
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anti-Mitogen-Activated Protein Kinase 7 (MAPK7) (AA 1-310) antibody
MAPK7 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 7 (MAPK7) (AA 185-419) antibodyMAPK7 Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 7 (MAPK7) (AA 411-556) antibodyMAPK7 Reaktivität: Human IHC, ELISA Wirt: Maus Monoclonal 8H1D5 unconjugated
anti-Mitogen-Activated Protein Kinase 7 (MAPK7) (pSer496) antibodyMAPK7 Reaktivität: Human, Maus WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 7 (MAPK7) (pSer731), (pThr733) antibodyMAPK7 Reaktivität: Human WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 7 (MAPK7) antibodyMAPK7 Reaktivität: Human WB, FACS, ICC Wirt: Kaninchen Monoclonal 24GB290 unconjugated Recombinant Antibody
anti-Mitogen-Activated Protein Kinase 7 (MAPK7) (AA 776-805), (C-Term) antibodyMAPK7 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB0919 unconjugated
anti-Mitogen-Activated Protein Kinase 7 (MAPK7) (AA 776-805) antibodyMAPK7 Reaktivität: Human WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 7 (MAPK7) (AA 401-500) antibodyMAPK7 Reaktivität: Maus, Ratte WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
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WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(ICC) 1:50-200 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Haltbarkeit
- 12 months
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- MAPK7 (Mitogen-Activated Protein Kinase 7 (MAPK7))
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Andere Bezeichnung
- ERK5
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Hintergrund
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Synonyms: BMK1, ERK4, ERK5, PRKM7, Mitogen-activated protein kinase 7, MAP kinase 7, MAPK 7, Big MAP kinase 1, BMK-1, Extracellular signal-regulated kinase 5, ERK-5, MAPK7
Background: Plays a role in various cellular processes such as proliferation, differentiation and cell survival. The upstream activator of MAPK7 is the MAPK kinase MAP2K5. Upon activation, it translocates to the nucleus and phosphorylates various downstream targets including MEF2C. EGF activates MAPK7 through a Ras-independent and MAP2K5-dependent pathway. May have a role in muscle cell differentiation. May be important for endothelial function and maintenance of blood vessel integrity. MAP2K5 and MAPK7 interact specifically with one another and not with MEK1/ERK1 or MEK2/ERK2 pathways. Phosphorylates SGK1 at Ser-78 and this is required for growth factor-induced cell cycle progression. Involved in the regulation of p53/TP53 by disrupting the PML-MDM2 interaction.
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Gen-ID
- 5598
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UniProt
- Q13164
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Pathways
- MAPK Signalweg, Neurotrophin Signalübertragung, Activation of Innate immune Response, cAMP Metabolic Process, Toll-Like Receptors Cascades, Negative Regulation of intrinsic apoptotic Signaling
Target
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