MYD88 Antikörper (N-Term)

Produktnummer ABIN2786657

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch MYD88 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Hund, Pferd, Kaninchen und Meerschweinchen.

Kurzübersicht für MYD88 Antikörper (N-Term) (ABIN2786657)

Target: MYD88 (Myeloid Differentiation Primary Response Gene (88) (MYD88))

Reaktivität: Human, Maus, Ratte, Hund, Pferd, Kaninchen, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MYD88 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MYD88 Antikörper

Bindungsspezifität: N-Term

Sequenz: YLEIRQLETQ ADPTGRLLDA WQGRPGASVG RLLELLTKLG RDDVLLELGP

Homologie: Dog: 77%, Guinea Pig: 77%, Horse: 85%, Human: 100%, Mouse: 75%, Rabbit: 85%, Rat: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against MYD88. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MYD88

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 296 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MYD88

Target: MYD88 (Myeloid Differentiation Primary Response Gene (88) (MYD88))

Andere Bezeichnung: MYD88

Hintergrund: This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways reg
Alias Symbols: MYD88D
Protein Interaction Partner: MYD88, IRAK4, IL1R1, IKBKG, SPOP, SYK, SASH1, TRAF6, SIAH2, SIAH1, PFKL, PRDX1, MDM2, MAL, SMAD3, MBIP, TLR7, TNFRSF13B, CD93, IKBKE, POLR1C, IL1RL1, FADD, USP7, TXN, BST2, SMURF1, LRRFIP2, UBC, SMAD6, IRF5, IRAK1, BTK, PELI1, STAP2, TNIP1, TRAF3, IRAK2,
Protein Size: 296

Molekulargewicht: 33 kDa

Gen-ID: 4615

NCBI Accession: NM_002468, NP_002459

UniProt: Q99836

Pathways: NF-kappaB Signalweg, TLR Signalweg, Neurotrophin Signalübertragung, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades