Phospholipase C beta 1 Antikörper (Middle Region)

Produktnummer ABIN2786397

Produktdetails anti-Phospholipase C beta 1 Antikörper

Target: Phospholipase C beta 1 (PLCB1) (phospholipase C, beta 1 (phosphoinositide-Specific) (PLCB1))

Bindungsspezifität: Middle Region

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund, Meerschweinchen, Kaninchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Phospholipase C beta 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: EAQSKRQEKL VEKHKEIRQQ ILDEKPKGEG SSSFLSETCH EDPSVSPNFT

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PLCB1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PLCB1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1173 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Phospholipase C beta 1

Target: Phospholipase C beta 1 (PLCB1) (phospholipase C, beta 1 (phosphoinositide-Specific) (PLCB1))

Andere Bezeichnung: PLCB1 (PLCB1 Produkte)

Hintergrund: The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction
Alias Symbols: FLJ45792, PI-PLC, PLC-154, PLC-I, EIEE12, PLC154, PLCB1A, PLCB1B
Protein Interaction Partner: TFCP2, CTBP2, CTBP1, CEP76, PLCB1, GNAQ, SLC9A3R1, GNA11, PCF11, UBC, KRIT1, SPTBN1, TRPC3, TRPM7, PARD6A, PARD3, RGS4, RGS12, MAPK3, PRKCD, PRKCA, MAPK1,
Protein Size: 1173

Molekulargewicht: 134 kDa

Gen-ID: 23236

NCBI Accession: NM_182734, NP_877398

UniProt: D3DW13

Pathways: WNT Signalweg, AMPK Signaling, Thyroid Hormone Synthesis, Inositol Metabolic Process, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, Proton Transport, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events, G-protein mediated Events